BREEDING OF A GLUTATHIONE OVERPRODUCING STRAIN
- VernacularTitle:谷胱甘肽高产菌株的选育
- Author:
Jianping JIA
;
Juanping QIU
;
- Publication Type:Journal Article
- Keywords:
Glutathione, Saccharomyces cerevisiae, Strain breeding, Irradiation, Mutant
- From:
Microbiology
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
A zinc chloride and ethionine resistant mutant 0 5Eth400 5 was o btained from its parent strain Saccharomyces cerevisiae 346 by UV and 60 Co ? ray tr e atment and rational screening The glutathione productivity of the mutant reach e d 165 96mg/L by flask culture, which was 350% higher than the parent strain, an d the glutathione content in the dried cells reached 19 76mg/g, which was 318 6% higher than the parent strain A desecend of only 10 7% in the glutathione yie ld of the mutant was observed after ten times of subculture Therefore, the obtai ned mutant is stable strain that is worthwhile to be studied further
