STREPTOMYCIN RESISTANCE MUTATION——A STUDY ON THE BREEDING OF HIGH NATAMYCIN-PRODUCING STRAIN
- VernacularTitle:链霉素抗性突变——纳他霉素高产菌株的选育研究
- Author:
Dongjing YANG
;
Guanqun CHEN
;
Wei CHEN
;
Min WANG
;
Lian DU
;
- Publication Type:Journal Article
- Keywords:
Streptomyces gilvosporeus, Method of streptomycin resistance screening, Muta genesis, Natamycin
- From:
Microbiology
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
A method of streptomycin resistance screening was applied to improve t he productivity of Natamycin by Streptomyces gilvosporeus(ATCC13326) The sp ores treated with UV light were regenerated on agar plates containing 0 6?g/mL stre p tomycin 122 streptomycin resistant(str) mutants were obtained The Natamycin y iel ds of 13 mutants were higher than the original strain The mutants with high Na t amycin productivity were screened at a high frequency(10 6%) The highest one that demonstrated 1 46 times that of the original strain in Natamy cin productivity was obtained
