ADHESION OF HEAT-KILLED BIFIDOBACTERIUM ADOLESCENTIS TO HUMAN COLORECTAL CARCINOMA CELL

VernacularTitle:灭活的青春双歧杆菌对人大肠癌细胞的粘附
Author: Yongzhi LUN ; Min HUANG ; Jieli YUAN ; Bai KANG ;
Publication Type:Journal Article
Keywords: Bifidobacterium,Intestines,Epithelium,Bact erial adhesion
From: Microbiology 1992;0(04):-
CountryChina
Language:Chinese
Abstract: The assay investigated mainly the adhesion phenomenon of heat killed Bifidoba cterium adolescentis DM8504 to human colorectal carcinoma cell line CCL 22 9 Moreover, the assay discussed the adhesion mechanism of Bifidobacterium Resu lts found heat killed bifidobacterium would be the same ability to adhere and c o lonize to human intestinal epithelial cells in vitro as live bifidobacterium, an d their adhesion had to depend on its spent culture supernatant(SCS) The adh esin of Bifidobacterium adolescentis was possibly lipoteichoic acid(LTA)w h ich existed on the cell wall of bacteria and was secreted into the SCS LTA bou nd to the heat resistant proteins of cell surface of bacteria, and extended out from the cell surface Moreover, the bifidobacterial adhesin rece ptor of intestinal epithelial cells was possibly saccharides or glycopolymers