Expressions of survivin and P53 in human non-small cell lung cancer and their relationship
- VernacularTitle:survivin、P53蛋白在非小细胞肺癌的表达及其相关性研究
- Author:
Jinghua WANG
;
Guiyuan LI
;
Chen WANG
;
Longbang CHEN
;
Henghui MA
;
- Publication Type:Journal Article
- Keywords:
survivin;
P53;
Immunohistochemistry;
Non small cell lung cancer
- From:
Journal of Medical Postgraduates
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: To investigate the expression and distribution of survivin and P53 in human non small cell lung cancer (NSCLC),and to evaluate the relationship between survivin and P53. Methods:The expression of survivin and P53 in 95 patients with NSCLC were examined using immunohistochemical methods (SP), and the relationship between them and clinicopathological parameters was analyzed. Results: The positive rates of survivin and P53 in NSCLC were 62% and 55.8% respectively, in the normal lung tissues nearby were 17% and 7% respectively( P