The determination of parathyroid hormone in the chronic renal failure and its clinical significances
- VernacularTitle:甲状旁腺激素测定在慢性肾功能衰竭中的临床意义
- Author:
Yufeng QIAN
;
Weimin CAI
;
- Publication Type:Journal Article
- Keywords:
Parathyroid hormone;
Chronic renal failure;
End stage renal failure;
Genetic polymorphism;
Two side immunoradiometric assay
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
The secondary hyperparathyroidism is one of the complications of chronic renal failure (CRF) and end stage renal failure (ESRD), and becomes more serious with the development of the primary disease. Parathyroid hormone (PTH) is considered as one of the biomarks of the development of renal failure. The purpose of this article will expound the physiological effects of the PTH, the causes and clinical significances of PTH rising in CRF and ESRD patients, the determination of PTH level, and the relationships between the increase of PTH and the polymorphism of CYP2D6, GSTT1,GSTM1.