THE STUDY ON DIFFERENCE OF PROTEIN EXPRESSIONS IN AN ANTIBIOTIC AGPM FERMENTATION PROCESS
- VernacularTitle:抗生素AGPM发酵过程中蛋白质表达差异的研究
- Author:
Jinyang NIU
;
Jianjun QIAO
;
Guibin CHEN
;
Jianyong ZHANG
;
Ying YUAN
;
- Publication Type:Journal Article
- Keywords:
Streptomyces regensis , AGPM, Proteome, Two dimensional gel electrophoresis
- From:
Microbiology
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
A new strain of Streptomyces regensis was isolated from soil to produce a novel antibiotic AGPM possessing a strong antitumor activity In order to study on the metabolic path of the novel antibiotic AGPM, the protein patterns from the strain of Streptomyces regensis at different culture period were analyzed by using two eimensional polyacrylamide gel electrophoresis Comparing with sample from growth phase, seventeen new protein spots were found in that from antibiotic production phase The results demonstrated that the special proteins might be related with the antibiotic AGPM biosynthesis from Streptomyces regensis
