The diagnostic value of sTFR and its compound parameters in the differential diagnosis of iron deficiency anemia and anemia of chronic diseases
- VernacularTitle:可溶性转铁蛋白受体及其复合参数在缺铁性贫血及慢性病贫血鉴别诊断中的意义
- Author:
Peng WU
;
Xuewen WANG
;
Yuzhou ZHUANG
;
Haining LIU
;
Ping SHI
;
- Publication Type:Journal Article
- Keywords:
Serum transferrin receptor;
Iron deficiency anemia;
Anemia of chronic disease
- From:
Journal of Medical Postgraduates
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: To clarify the diagnostic value of sTFR and its compound parameters sTFR/SF, sTFR/logSF in the differential diagnosis of IDA, ACD and CDID. Methods: Forty nine anemia patients were classified into IDA, ACD and CDID by clinical presentations and the laboratory results. The serum concentration of sTFR was detected by ELISA. The difference of sTFR, sTFR/SF, sTFR/logSF and routine parameters in the three groups and the correlation among sTFR and routine parameters were analyzed. Using ROC curve, the diagnostic value of these parameters in the differential diagnosis of the three diseases were compared. Results: The serum concentration of sTFR in the IDA, ACD and CDID were (50.8?8.2)nmol/L, (33.5?6.9)nmol/L and (22.7?9.9)nmol/L,respectively. The differences among three groups were significant( P