The clinical observation of rocuronium bromide in pantients with hepatic cirrhosis
- VernacularTitle:罗库溴铵用于肝硬化患者静脉麻醉的临床观察
- Author:
Yongguang WANG
;
Jian LIU
;
Lidong ZHANG
;
- Publication Type:Journal Article
- Keywords:
Neuromuscular block;
Rocuronium;
Hepatic corrhosis
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To observe the characteristics of rocuronium bromide in cirrhotic patients. Methods:Six healthy patients and six patients with hepatic cirrhosis undergoing intraabdominal operation were studied. Rocuronium 0.6 mg/kg was given to all of the patients,and the twitch high of adductor pollicis muscle was recorded using NMT mechanosensor (Datex Ohmeda). The time of onset, T 1 Maximum depression, the clinical duration of initial dose, the clinical duration of repeated maintenance doses and the spontanous recovery index were observed. Results:The time of onset was markedly prolonged in the cirrhotic compared with the healthy group( P
