A pathologic study of sinusoid-lining endothelial cells in liver disease
- VernacularTitle:肝窦内皮细胞在肝病中的病理学研究
- Author:
Jie MA
;
Xiaojun ZHOU
;
- Publication Type:Journal Article
- Keywords:
Sinusoid lining endothelial cell;
Chronic liver disease;
Hepatocellular carcinoma;
Immunophenotype;
Capillarization
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Sinusoid lining endothelial cell(SEC) of the liver is a group of cells different from vessel lining endothelial cells with high heterogeneity characteristics, it shows many biological functions in normal liver and plays a role in liver injury caused by acute and chronic liver diseases as well as fibrogenesis. Increasing attention has been paid to the capillarization in hepatocellular carcinoma in recently years, some studies showed that SEC is attributed to the formation of capillarization with changes of the immunophenotype, such as expression of CD34.The pathological study of SEC on liver disease was briefly reviewed in this paper.
