A CYTOTOXIC METABOLITE OF STREPTOMYCES SP. SC120
- VernacularTitle:链霉菌SC120细胞毒活性代谢产物的研究
- Author:
Jidong WANG
;
Xiaoyi WEI
;
Xiru ZHU
;
Haihui XIE
;
Yizhu CHEN
;
- Publication Type:Journal Article
- Keywords:
Antibiotics, Streptomyces , Pimprinine, Cytotoxicity
- From:
Microbiology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
During the course of the investigation of the antifungal metabolites against Peronophythora litchii from the fermentation broth of Streptomyces sp SC120, an antibiotics that exhibited the cytotoxicity to CNE 2 was isolated By spectral (UV, IR, HRMS, 1H NMR, 13 C NMR, 1H 1H COSY, HMQC and HMBC) analyses, its structure was identified as pimprinine The cytotoxicity of pimprinine to CNE 2 was reported for the first time