RESEARCH OF HUMORAL IMMUNITY AGAINST CANDIDA ALBICANS INFECTION
- VernacularTitle:体液免疫抗白念珠菌感染的研究
- Author:
Ying-Yuan FU
;
Bing MO
;
Xiao-Ping ZENG
;
Nan-Zhen KUANG
;
Zhi ZHANG
;
- Publication Type:Journal Article
- Keywords:
Candida albicans ,Humoral immunity
- From:
Microbiology
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the role of anti- C. albicans IgY and serum in protection of C. albicans infection of several animal models. To develop three animal models of C. albicans infection: a burned rat model of C. albicans infection, a mouse model of vaginal candiasis and a immunosuppression mouse model of C. albicans infection. And we compared the contribution of anti- C. albicans IgY and serum to the clearance of the C. albicans in three animal models of C. albicans infection. Anti- C. albicans IgY can protect against C. albicans infection in a burned rat model of C. albicans infection and a mouse model of vaginal candidiasis. The serum can effectively protect the mice from disseminated candidiasis in a immunosuppression mouse model. Humoral immunity component involving anti- C. albicans IgY and serum protect against C. albicans infection in a burned rat model of C. albicans infection ,a mouse model of vaginal candidiasis and a immunosuppression mouse model of C. albicans infection.
