OPTIMIZATION OF THE MEDIUM AND PROCESS PARAMETERS IN BATCH AMINOGLYCOSIDE ANTIBIOTIC JI-20A FERMENTATION
- VernacularTitle:氨基糖甙类抗生素JI-20A发酵培养条件的研究
- Author:
Jian-Feng CHEN
;
Yuan-Xing ZHANG
;
Yang-Hao GUO
;
Jian-Ji LI
;
- Publication Type:Journal Article
- Keywords:
Antibiotic JI-20A, Aminoglycoside antibiotics, Fermentation, Medium, Optimization
- From:
Microbiology
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The medium and process parameters were optimized in batchaminoglycoside antibiotic JI-20A fennentation. The optimal medium consists mainly of comstarch 60g/L, peanut meal 30g/L, com slurry 8g/L, maltose 10g/L, inorganic compound and amylase moderate , methionin 1g/L and cobalt chloride 6?g/mL. It was significant to adjust medium pH after autoclaving and oxygenate the fennentation medium for the cell growth and JI-20A product.
