Studies on antineoplastic constituents from chinese marine mollusc sea hare(Ⅰ)
- VernacularTitle:中国产海兔抗肿瘤活性成分研究(Ⅰ)
- Author:
Houwen LIN
;
Chun ZHANG
;
Yanghua YI
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Sea hare;
Notarchus leachii cirrosus;
Antineoplastic activies;
Monoterpenes
- From:
Chinese Journal of Marine Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Two active compounds were isolated from chinese marine mollusc sea hare (Notarchus leachii cirrosus) by bioassay guided method with conidia of Pyricularia oryzae , and by a combination of extraction and purification with suitable solvent as well as multiple column chromatographies. Their structures were elucidated as (7 E) 1 acetoxy 8 chloro 7 (dichloromethyl) 3 methyoct 7 en 4 one (Ⅰ), (7 Z) 1 acetoxy 8 chloro 7 (dichloromethy l) 3 methyoct 7 en 4 one (Ⅱ). All compounds were obtained for the first time from this specimen and showed significant antineoplastic activities in vitro .
