Study of synergistic effects of Spirulina platensis on inducing IL-2
- VernacularTitle:螺旋藻不同组份对小鼠脾细胞分泌IL-2的促进作用
- Author:
Min LI
;
Weili HUANG
;
Ying YE
;
Wenhan LIN
;
Hongzheng FU
;
Jingrong CUI
;
- Publication Type:Journal Article
- Keywords:
Spirulina platensis,;
IL 2;
MTT
- From:
Chinese Journal of Marine Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
It has been shown that Spirulina platensis can regulate imminological functions.We report here that crude extract and purified components (phycocyanin and polysaccharide) from Spirulina platensis can induce secretion of IL 2 in splenocyte of BALB/C mice by means of MTT method.In the present study,we showed that all experimental components can't enhance proliferation of CTLL which was used in MTT method,but induce IL 2 secretion in splenocyte of BALB/C mice in three different concentration (0.01,0.1,1 g?L -1 ).Indeed the purified components especially phycocyanin part showed stronger IL 2 inducing activity than the crude one.IL 2 level was grow up when the incubation time of splenocyte and Spirulina platensis increased.In the concentration of 1 g?L -1 ,detected Spirulina platensis in our study assist IL 2 inducing of ConA (2mg?L -1 ) in splenocyte of BALB/C mice.
