Chemical modification of lead compounds by monasacchrides and their derivatives
- VernacularTitle:糖类对先导化合物的化学修饰及其在药学中的应用
- Author:
Xinmei FU
;
Tao JIANG
;
Kuiqi WANG
;
Daishu ZUO
;
Huashi GUAN
;
- Publication Type:Journal Article
- Keywords:
saccharides and their derivatives;
lead compounds;
chemical modification
- From:
Chinese Journal of Marine Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
As a summary of the research progress of chemical modification of lead compounds by saccharides and their derivatives, this article studies the linkage style of saccharides with lead compounds and bioactivity changes of the modified lead compounds. The result shows that the modified lead compounds can decrease the toxicity and side effect efficiently, and enhance the pharmacal effect. Therefore, it is a promising research project to modify lead compounds by saccharides.
