Effect of glipizide on insulin sensitivity in patients with NIDDM
- VernacularTitle:Glipizide对非胰岛素依赖型糖尿病患者胰岛素敏感性的影响
- Author:
Minxiang LEI
;
Hanwen WU
;
Chusheng CHAO
;
Min HUI
;
Eryuan LIAO
;
Zhiguang ZHOU
;
- Publication Type:Journal Article
- Keywords:
Glipizide;
Insulin sensitivity;
Minimal model
- From:
Chinese Journal of Diabetes
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of glipizide on SI、SG、KG、Iarea 0～20min、FBG、FINS with minimal model in non-insulin-dependent diabetes meIlitus were observed.The results showed SI、SG、KG、Iarea 0～20min were lower and FBG was higher in NIDDM than these in normal subjects before glipizide therapy.After two weeks of glipizide therapy,FBG was decreased and SI、SG、KG、Iarea 0～20min were increased.These data suggested that glipizide not only had the effect on stimulating islet ?-cell secretion,but also improving insulin sensitivity and glucose effectiveness.
