RELEASE OF COLONY-STIMULATING FACTOR INDUCED BY ENDOTOXIN FROM BACTEROIDES MELANINOGENICUS ATCC 25845
- VernacularTitle:产黑色素类杆菌ATCC25845内毒素对小鼠集落刺激因子的诱生活性
- Author:
Jun YIN
;
Yu ZHANG
;
Weiming YU
;
Junnan SHI
;
- Publication Type:Journal Article
- Keywords:
Bacteroides melaninogenicus;
Endotoxin;
Colony-stimulating factor
- From:
Microbiology
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Present study investigated the effect of endotoxin from Bacteroides melaninogenicus ATCC 25845 on release of colony-stimulating factor (CSF)in mice. The bone marrow cells were cultured in semisolid agar medium,the number of colonies was as a level index of CSF. The results showed that as much as 0.1?g endotoxin could induce the release of CSF,moreover, The level of CSF increased with dose of endotoxin untill 50 ?g. The colony-stimulatin factor level of B. melaninogenicus endotoxin was 66.6?8.5(CFU-C). This endotoxin showed significant effect on bone marrow cells of mice.
