STUDIES ON THE DIAGNOSIS OF HUMAN FILARIASIS BY INDIRECT FLOURESCENT ANTIBODY TEST(IFAT) AND IMMUNOENZYMATIC STAINING TECHNIQUE(IEST) WITH HOMOLOGOUS AND HETEROLOGOUS ADULT FILARIAL ANTIGENS
- VernacularTitle:同种和异种丝虫成虫抗原间接荧光抗体试验及免疫酶染色试验诊断丝虫病的研究
- Author:
Yunhe LI
;
Yonde HU
;
Wenmei XU
;
Zongquan WU
;
Guangbao YANG
;
Shuilong YIN
;
Wei LUO
;
Wei GONG
;
- Publication Type:Journal Article
- From:
Chinese Journal of Parasitology and Parasitic Diseases
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
This article deals with the diagnostic values of IFAT and IEST in human filariasis with both frozen sections of Brugia malayi and Setaria cervi adult worms as antigens. The average positive and the false positive rates of IFAT with two antigens were 84.9-97.1%(45/53-102/105)and 2.9-9.7%(1/35-3/31) respectively, while no cross-reaction was observed in subjects infected with ascaris or hookworm. The average positive and the false positive rates of IEST with two antigens were 94.3-94.9% (99/105-56/59) and 0-2.9% (0/35-l/35) respectively. Both IFAT and IEST with two antigens for the diagnosis of human filariasis were considered to be of higher sensitivity and specificity, frozen sections of adult Setaria cervi being more economical and effective.