Determination of Ephedrine Hydrochloride in Zhike Pingchuan Tangjiang by HPLC
- VernacularTitle:止咳平喘糖浆中盐酸麻黄碱的HPLC测定
- Author:
Xin-Hui GUO
;
Fen WANG
;
Jun-An CAI
;
- Publication Type:Journal Article
- Keywords:
Zhike Pingchuan Tangjiang;
ephedrine hydrochloride;
HPLC
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the method for detemining the content of ephedrine hydrochloride in Zhike Pingchuan Tangjiang by HPLC. Methods Diamonsil ODS1 C_(18) Column was used with acetonitrile -0.1% phosphoric solution (with 0.1% triehylamine) (3 : 97) as the mobile phase, the detection wavelength as 205 nm, and flow rate was 1.0 mL/min. Results The calibration curve was linear at the range of 0.12～ 0.96 ?g for ephedrine hydrochloride and linear equation was Y= 109759X+3792.8, r=0.9998. The average recovery was 98.4% and RSD was 0.87% (n =5). Conclusion This method was simple, accurate and proper, with good reproducibility. It can be used for quantitative analysis of ephedrine hydrochloride in Zhike Pingchuan Tangjiang.
