Clinical Effect of Skeletal Metastases Treated by Chemotherapy Combined with Ibandronate
- VernacularTitle:伊班膦酸钠联合化疗治疗转移性骨肿瘤
- Author:
Haixia PAN
;
Xueqiang ZHU
;
Ying DENG
;
Gang REN
;
Honglin HU
;
Lan YANG
;
Hao LIU
;
- Publication Type:Journal Article
- Keywords:
Ibandronate;
Chemotherapy;
Skeletal metastases
- From:
Chinese Journal of Pharmacoepidemiology
2007;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the therapeutic effect of the treatment with intravenous(Ⅳ)ibandronate com- bined with chemotherapy on patients with skeletal metastases.Method:138 patients with skeletal metastases were randomly divided into ibandronate group combined with chemotherapy(68 cases)and simple chemotherapy group(70 cases).The controlled group took a standard chemotherapy project but combined the treatment group took a chemotherapy project plus ibandronate.In a week after the chemotherapy,68 cases of the treatment group were treated with ibandronate 4mg in NS 500ml by intravenous infusion once 4 weeks for 3 months.The effect was evaluated when the three cycles finished.Result: There was a statistical difference(P