Research of the Immunotoxicity of Shuanghuanglian Injection
- VernacularTitle:注射用双黄连的免疫毒性研究
- Author:
Jinfei LI
;
Yang LI
;
Qi CHEN
;
Zhaohui CHENG
;
Shun TANG
;
- Publication Type:Journal Article
- Keywords:
Shuanghuanglian Injection;
Chlorogenic acid;
Sensitization
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the allergic reaction of Shuanghuanglian Injection(SI)and chlorogenic acid.Meth- ods The sensitization of SI was evaluated by observed the systemic active allergic reaction on guinea pigs.The homogeneous and heterogenic passive skin allergic reactions in rats,mice and guinea pigs were observed to compare the sensitationz of SI and chlorogenic acid.Results The possibility of SI causing allergic reaction was higher than that of chlorogenic acid.Con- clusion It is suggested that the possibility of SI as a compound arising adverse reactions be higher than that of chlorogenic acid.