The Significance of Buckwheat Chaff Stuffed Pillow on the Sensitization to Buckwheat in Asthmatic Children.
- Author:
Soo Young LEE
1
;
Ki Soo PAI
;
Ki Sun LEE
;
Gye Ree JEON
;
Chang Ho HONG
Author Information
1. Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.
- Publication Type:Original Article
- Keywords:
Buckwheat flour;
Buckwheat chaff stuffed pillow (BCP);
Childhood asthma;
BF specific IgE;
BCP elimination-provocation test
- MeSH:
Asthma;
Child*;
Eating;
Fagopyrum*;
Flour;
Follow-Up Studies;
Humans;
Hypersensitivity;
Immunoglobulin E;
Inhalation;
Pyroglyphidae
- From:Pediatric Allergy and Respiratory Disease
2000;10(4):290-298
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Buckwheat flour (BF) is known as a potent food allergen. Its sensitization usually occurs by ingestion, but also by inhalation due to occupational or domestic exposure. We underwent this study to identify an effect of buckwheat chaff stuffed pillow (BCP) exposure on sensitization to BF and clinical BF allergy in asthmatic children. METHOD: We obtained detailed history of BCP exposure in 36 asthmatic children (aged 0.7-14.2 years). We also performed RIA for specific IgE, BCP-elimination-provocation test. All subjects were divided into 3 groups, Group I (continuous BCP exposurers, n=13), Group II (previous exposurers, n=11), and Group III (non-exposurers to BCP, n=12) and all subjects had no history of ingestion of BF containing foods. RESULTS: In the 13 Group I cases, the durations of BCP exposure were 1-6 years, and 8 of them were users of BCP themselves, 5 were indirect exposurers by family members' BCP. The positive rates of BF specific IgE were 92.3, 36.4% and 8.3% in the Group I, II and III, respectively (Chi-square test, P<0.05). While the positive rates of house dust mites specific IgE were not significantly different among three groups. Twelve out of 13 Group I cases sensitized to BF, and 9 of those 12 were not sensitized to house dust mites. Eight out of 13 Group I cases were positive in BCP elimination-provocation test, during 6-24 month follow-up periods, 7 of them were managed effectively by BCP elimination only. CONCLUSION: Taken together, a small amount of BF attached to BCP can induce BF sensitization and BCP can be a major cause of childhood nocturnal asthma.
