Logistic Analysis of the Infectious ODDS Risks of Anticancer Drugs in GI Cancer Patients with Chemotherapy Regiments
- VernacularTitle:抗肿瘤药与消化道肿瘤化疗患者感染风险的Logistic回归分析
- Author:
Dazhi WANG
;
Juan WANG
;
Shuyu ZHANG
;
Xiaolu YANG
;
- Publication Type:Journal Article
- Keywords:
Antitumor drugs;
GI cancer;
Infection;
Logistic analysis
- From:
Chinese Journal of Pharmacoepidemiology
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the infectious ODDS risks of anticancer plant alkaloids and other anticancer drugs in GI cancer patients with chemotherapy regiments.Method:2384 profiles of cancer patients agreeable with studying condition were collected.All the profiles were evaluated with different variants,and then these variants were analyzed with the logistic liner.Result:The line values of ages,days in hospital,insurances,alkylating agents,platinum antitumor com- pounds and other antitumor drugs were 0.010,0.147,-0.361,-0.930,-0.390,and-1.306.Conclusion:The infection OR of the ages and days in hospital increased OR factors and the medical insurances decreased OR factors.Antitumor antibiot- ics,antimetabolites,plant alkaloids had their higher infectious risks than platinum antiturnor compounds,alkylating agents and other antitumor drugs did in GI cancer patients with chemotherapy regiments.