Association of changes in frequency of peripheral natural killer T cells with nonalcoholic fatty liver disease
- VernacularTitle:外周血自然杀伤T细胞比例变化与非酒精性脂肪性肝病的关系
- Author:
Ze-Jun WANG
;
Chengfu XU
;
Lei XU
;
Zhaohui YU
;
Youming LI
;
- Publication Type:Journal Article
- Keywords:
Fatty liver;
Killer eells,natural;
Risk factors
- From:
Chinese Journal of Digestion
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of changes in peripheral natural killer T(NKT) cells and fatty liver disease(NAFLD).Methods Peripheral blood samples were obtained from 60 NAFLD patients and 60 age and gender matched healthy controls.The frequency of peripheral NKT cells was detected by flow cytometry.The differences of clinical presentation and laboratory data in two groups were analyzed.The risk factors of NAFLD were screened by Logistic regression analysis. Results NAFLD patients had lower frequency of peripheral NKT cells than healthy controls [median fre- quency was 1.12%(IQR0.87%～1.54%)in patients vs.1.48%(1.23%～1.98%) in controls,P
