Effectiveness of sirolimus-eluting stents in emergency percutaneous coronary intervention
- VernacularTitle:急诊经皮冠状动脉介入治疗中应用雷帕霉素洗脱支架的疗效观察
- Author:
Ru-Hui LIU
;
Ming-Zhong ZHAO
;
Yang LIU
;
Wen-Lin MA
;
Bing DENG
;
Jia-Hong XU
;
Jin-Fa JIANG
;
Da-Yi HU
;
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Angioplasty,transluminal,percutaneous coronary;
Drug eluting stent
- From:
Chinese Journal of General Practitioners
2005;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy and safety of applying sirolimus-eluting stents in emergency percutaneous coronary intervention (PCI) for the patients with acute myocardial infarction (AMI).Methods In total,220 patients with AMI were enrolled in this study at Shanghai Tongji Hospital, divided into two groups,one with bare-metal stent and the other with sirolimus-eluting stent.Cardiovascular fatality,major adverse cardiac events (MACE) and target vessel revascularization (TVR) were observed one and six months after PCI in the two groups.Results There was no significant difference in overall fatality and MACE in the 1~(st) or 6~(th) months after PCI between the two groups.Three cardiogenic deaths occurred in bare-metal stent group with a fatality of 2.8 percent,and five deaths in sirolimus-eluting stent group with a fatality of 4.5 percent in six months after PCI.However,rate of restenosis in those with sirolimus-eluting stents was significantly lower than that of bare-metal stents (6.0 percent vs 16.1 percent,P
