Effects of electroacupuncture on the expression of microvascular endothelial ICAM-1 and P-selectin in rats with cerebral ischemia-reperfusion
- VernacularTitle:电针对脑缺血再灌注大鼠脑微血管内皮细胞间黏附分子-1和P-选择素表达的影响
- Author:
Qing-Ju MAO
;
Hou-Xiu LI
;
Li-Hong KONG
;
Bang-Guo CHEN
;
- Publication Type:Journal Article
- Keywords:
Cerebral ischemia reperfusion;
Electroacupuncture;
Intercellular adhesion molecule-1;
P-selectin;
Immunal regulation
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effects of electroacupuncture on the endothelial tissues of microvessels in the basal ganglia in the rats with cerebral ischemia-reperfusion.Methods The MCAO model was established by using Longa's method.The immunohistochemistry SABC(strepto-avidin-biotin-peroxidase complex) method was employed to detect the expression of ICAM-1,P-selectin in the microvessel of rats'ipsilateral basal gan- glia.Results The number of positive ICAM-1 and P-selectin endothelial cells of model group were significantly in- creased,as compared to normal group and sham operated group(P