The protective effects and mechanism of Green Tangerine induced hypertension and mild hypothermia on brain infarction during focal cerebral ischemia and reperfusion
- VernacularTitle:亚低温干预联合青皮升压对局灶性脑缺血再灌注损伤的保护作用及相关机制探讨
- Author:
Hong CHEN
;
Kun QIAN
;
Fei ZENG
;
Xiao-Lin HUANG
;
- Publication Type:Journal Article
- Keywords:
Cerebral ischemia,reperfusion;
Mild hypothermia;
Hypertension;
Local cerebral glucose utilization
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effects of Green Tangerine induced hypertension and mild hypothermia on focal cerebral ischemia and reperfusion and local cerebral glucose utilization(LCGU)in the in- farction rim in rats.Methods A total of 64 rats were used and randomly divided into a control group,a Green Tan- gerine induced hypertension group,a mild hypothermia group and a combination therapy group.The neurologic defi- cits,infarct size and LCGU were observed in the rats with focal cerebral ischemia and reperfusion.Results Com- pared with the control group,the neurologic deficits(P
