Retrospective study of chemoradiotherapy based on cisplatin compared with radiotherapy alone for cervical cancer
- VernacularTitle:单纯放疗与以顺铂为主的同步放化疗治疗子宫颈癌的临床效果对比分析
- Author:
Chao HAN
;
Wei-Min KONG
;
- Publication Type:Journal Article
- Keywords:
Cervix neoplasms;
Cisplatin;
Antineoplastic combined chemotherapy protocols;
Radiotherapy
- From:Chinese Journal of Obstetrics and Gynecology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the treatment effects and side events between chemoradiotherapy and radiotherapy alone for patients with primary cervical cancer.Methods Totally 197 patients with primary cervical cancer in our hospital from 2000 to 2006 were studied.They were divided into two groups: radiotherapy alone(RT)or cisplatin-based chemoradiotherapy(CRT).Group of RT included 100 patients who received external irradiation by ~(60)Co and intracavitary irradiation by ~(192)Ir.Group of CRT included 97 patients who received cisplatin-based chemoradiotherapy.The RT regimen was the same as group RT.Results The local control(CR+PR)in two groups had no statistic difference(P=0.500).The total 5 year survival rate in the two groups were 82% and 79%,with no significant difference(P=0.177);however,there was a significant difference for stage Ⅲ squamous cell carcinoma of the cervix,the 5 year survival rate being 56% and 84%,respectively(P
