The effect of physical training on insulin resistance in patients with chronic heart failure
- VernacularTitle:运动训练对慢性心力衰竭患者胰岛素抵抗的影响
- Author:
Zhao-Qiang DONG
;
Yi-Meng DU
;
Wan-Cai CAO
;
Wei-Dong JIANG
;
Qun WANG
;
Qing-Hua LU
;
Le JIANG
;
- Publication Type:Journal Article
- Keywords:
Heart failure;
Insulin resistance;
Physical training
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate insulin resistance and the effect of physical training on it in the pa- tients with chronic heart failure (CHF). Methods One hundred and twenty NYHAⅡ-ⅢCHF patients were ran- domly divided into a training group( n = 65 ) and a routine therapy group (n = 55 ). Another 35 healthy subjects were recruited as control group. All the patients were treated with routine anti-CHF drugs, and the training group patients had received physical training twice a day in addition. The HOMA-IR, insulin sensitivity index (ISI) , left ventricu- lar ejection fraction (LEVF), left ventricular fractional shortening( LVFS), 6-minute walking distance, heart rate and mean blood pressure were compared between the training and routine therapy groups before and after physical ex- ercise in both groups, and a comparison was made between the patients and the controls before the intervention with regard to HOMA-IR and ISI. Results Comparing with control group, ISI was reduced while the HOMA-IR in- creased (P
