Fetal cardiac function in fetal cardiac bypass
- VernacularTitle:胎羊心脏转流对胎羊心功能的影响
- Author:
Cheng-Bin ZHOU
;
Jin-Fang ZHANG
;
Jian ZHUANG
;
Shusheng WEN
;
Yanying LIU
;
Xiaohua ZHANG
;
- Publication Type:Journal Article
- Keywords:
Extracorporeal circulation;
Ventricular function Placental function;
Fetal lamb
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
1995;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of fetal lamb cardiac bypass on the fetal cardiac function.Methods Eight ewes at gestation of 120 to 140 days have nine fetus which were randomly divided into control group (n = 4) and fetal bypass group (n = 5). Control group underwent sham procedure that fetal stemotomy was performed.Bypass group underwent fetal cardiac bypass with cen- trifugal pump and placenta for 30 minutes.Fetal mean blood pressure,heart rate and bleed gas data were recorded before bypass,30 minutes during bypass,1 hour after cessation of bypass,2 hour after cessation of bypass.Tei index of two ventricles and pulse index of umbilical arteries were recorded with ultrasonography.Plasma troponin I was assayed.Ultrastructure of fetal myocardium was recorded,Results Fetal mean blood pressure and heart rate of two groups have no changes during the experiment time.The umbilical pulse index of bypass group elevated significantly compared with control group (P
