Monitoring of transpulmonary thermodilution technique for quantification of extravascular lung water in dogs with ALI
- VernacularTitle:经肺热稀释技术对急性肺损伤犬血管外肺水的监测
- Author:
Lu LIANG
;
Jun XU
;
Zhong WANG
;
Xue-Zhong YU
;
Sui MA
;
- Publication Type:Journal Article
- Keywords:
Transpulmonary thermodilution technique;
Extravascular lung water;
Pulse contour cardiac output;
Acute lung injury
- From:
Chinese Journal of Emergency Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the reliability of transpulmonary thermodilution technique,for the quantification of extravascular lung water.Method Eighteen dogs were randomly divided into 3 groups:normal group(n=6),ALIp(acute lung injury caused by pulmonary monary origin causes)group(n=6)and a ALIexp(acute lung injury caused by extra-pulmonary origin causes)(n=6).ALI_(exp)model was prepared by intravenous injection of injection of oleie acid.ALI_p model was made by inhalation of detergent.Extravascular lung water(EVLW)was measured by PiCCO monitor(PULSION,Germany)before and immediately after the intratracheal introduction of normal saline into the alveoh of lungs of normal and ALI dogs.Results The EVLW of the normal group was(254.5?13.0)mL.The volume of the normal between pre-and postinstillation(?EVLW) was approximate to the volume of normal saline instilled with a good correlation(r=0.986,P