Energy metabolism in patients with chronic viral hepatitis and posthepatitic cirrhosis
- VernacularTitle:慢性肝炎和肝炎后肝硬化患者能量代谢的研究
- Author:
Shu-Qing YU
;
Qing-Hua MENG
;
Yu-Xian LI
;
Yan-Mei FENG
;
Ming-Mei NI
;
Jin-Huan WANG
;
Xin WANG
;
- Publication Type:Journal Article
- Keywords:
Hepatitis,chronic;
Liver cirrhosis;
Energy metabolism;
Energy intake
- From:
Chinese Journal of General Practitioners
2005;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the pattern of energy metabolism and nutrients intake in patients with chronic viral hepatitis and posthepatitic cirrhosis to effectively direct their nutrition therapy.Methods Resting energy expenditure (REE) was measured with open-circuit indirect Jorimetry in 60 patients with chronic viral hepatitis and 60 patients with posthepatitic cirrhosis.Their normal basal energy expenditure (BEE) was predicted by Harris-Benedict equation and energy intake (EI) was determined by diet recall. Correlation between REE and indicators for nutrition assessment was analyzed.Results REE was (77? 21) kJ?kg~(-1)?d~(-1) in 60 patients with pusthepatitic cirrhosis,significantly lower than BEE[(95?16) kJ? kg~(-1)?d~(-1)(P0.05,and their EI was (127?34) kJ?kg~(-1)?d~(-1),1.41?0.43 times as REE,in which PROI was (1.02?0.29) g?kg~(-1)?d~(-1),1.31?0.61 times as PROE (0.87?0.34) g?kg~(-1)?d~(-1),also indicating a negative nitrogen balance (-2.02?4.07).REE,EI and intake of three nutrients,serum level of albumin and prealbumin (PA) and body weight significantly decreased in patients with posthepatitic cirrhosis,as compared to those in patients with chronic viral hepatitis (P
