Effects of different courses of hyperbaric oxygenation on proximal femur after high dosage of corticoid application in rat model
- VernacularTitle:高压氧对大剂量激素用药后大鼠股骨近端组织的影响
- Author:
Ji-Jun ZHAO
;
Shu-Hua YANG
;
Yong HU
;
Shu-Nan YE
;
Yong LIU
;
Ben LIU
;
- Publication Type:Journal Article
- Keywords:
Hyperbaric Oxygen;
Glucocorticoid;
Femur;
Bone morphogenetic protein;
Bone morphogenetic protein receptor
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Group A,the differences among the three groups were statistically significant(P0.05). TCR,CCR,DAP,OD,BRC in Groups B and C showed trends of increasing,the differences in terms of the contents of BMP-RⅠamong the 3 phases were statistically significant(P0.05);the ER in Group B and C showed a trend of decreasing,thee difference between 4- and 8-week and 4- and 12-week were signifieantly dif- ferent(P0.05).Conclusion After application of glucocorticoid for a short term,pathological changes maintained and showed trends of inereasing in early stage.HBO can reverse these changes.The outcome of 3-course HBO therapy is better than that of 1-course therapy.
