Endoscopic submucosal dissection in treatment of large flat gastric lesions
- VernacularTitle:内镜黏膜下剥离术治疗胃巨大平坦病变
- Author:
Ping-Hong ZHOU
;
Li-Qing YAO
;
Wei-Feng CHEN
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Endoscopy;
Biopsy;
Gastric mucosa
- From:
Chinese Journal of Digestion
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic value of endoscopic submucosal dissection(ESD) for large flat gastric lesions.Methods Large flat gastric lesions (≥2cm ) were dissected with a curved needle knife following:①injecting normal saline into the submucosa to separate the lesion from the mus- cle layer;②pre-cutting the surrounding mucosa of the lesion,and③dissecting the connective tissue of the submucosa under the lesion.Results Five flat gastric lesions ranged from 2.0 to 5.0 cm were re- moved successfully.Three located in the antrum,1 in the body and 1 in the incisure.The procedure time ranged from 80 to 120 min .Average blood loss was about 100 ml.The bleeding was controlled by elec- trocoagulation,argon plasma coagulation and clip.One patient had delayed bleeding after ESD.There was no perforation.There were clear resection margins confirmed by pathology in all 5 cases.The patients were followed up for 1-6 months .There were no recurrence with complete healing of original lesions.Conclusions ESD is a useful endoscopic method in treating large flat gastric lesion.It can com- pletely remove large lesion and provide precise pathological diagnosis.
