Use of iodixanol in coronary intervention for patients with diabetic renal insufficiency
- VernacularTitle:碘克沙醇在糖尿病伴肾功能异常患者冠状动脉介入治疗中的应用
- Author:
Hong LIU
;
Shu-Zheng LV
;
Yun-Dai CHEN
;
Xiao-Fan WU
;
Yuan ZHOU
;
Chang-Jiang GE
;
- Publication Type:Journal Article
- Keywords:
Iodixanol;
Diabetes mellitus;
Kidney failure
- From:
Chinese Journal of General Practitioners
2005;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety of coronary intervention using iodixanol in patients with diabetic renal insufficiency.Methods Clinical data of 97 patients with diabetic renal insufficiency undergoing coronary intervention during June 2004 to June 2006 were retrospectively analyzed,50 of them with iodixanol,an iso-osmolar contrast medium (iodixanol group),and 47 with iopromide,a hypotanic contrast medium (iopromide group).Judkin's coronary angiography showed 167 diseased vessels in the patients,65 in anterior descending branches,44 in circumflex branches,and 58 in right coronary arteries. Levels of serum creatinine and blood urea nitrogen were determined before percutaneous coronary intervention (PCI),on the day of the procedure,the 3rd and 7th days after PCI,respectively,as well as radiocontrast media-induced nephropathy (CIN) was observed.Results Totally,192 drug-eluting stents were successfully implanted in 167 diseased vessels,and all patients' angina pectoris symptom disappeared soon after the procedure,with a full success.No acute or subacute stent thrombosis and major adverse cardiac events (MACE) occurred.Two patients (4%) in iodixanol group and 10 (21%) in iopromide group got CIN,with a statistical significance (P
