Research on the correlation between lupus erythematosus cell and diseases activity in patients with systemic lupus erythematosus
- VernacularTitle:系统性红斑狼疮细胞与其病情活动性的相关性研究
- Author:
Mai-Gui YANG
;
Yang YANG
;
Wen-Ke CAI
;
Zhu-Ying ZHANG
;
Shan-Luan ZHENG
;
Ai-Lin FAN
;
Ling QU
;
Xiao-Ming WEI
;
Xiao-Ke HAO
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Autoantibodies;
Lupus cells;
SLEDAI
- From:
Chinese Journal of Rheumatology
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the morphologic changes of peripheral blood lupus cell in patients with systemic lupus erythematosus and investigate its relationship with disease activity in systemic lupus ery- thematosus.Methods Modified classical blood clotting method to observe the morphological changes of pe- ripheral blood lupus cells in 80 cases with systemic lupus erythematosus.Fifty cases were in active stage,and 30 cases were in stable stage.Comparison of serum autoantibody,complement and SLEDAI were also carried out.Results There was significant association between lupus cells in special morphous and autoantibody, such as anti-double-stranded DNA antibody,anti-nucleosome antibodies,complement C3、C4 and SLEDAI(r= 0.588,P=0.056:r=0.759,P=0.135;r=-0.648,P=0.058;r=-0.589,P=0.057,r=0.686,P
