Adult-onset Still's disease and acute severe hepatic lesion
- VernacularTitle:成人Still病与急性重度肝损害
- Author:
Li MA
;
Zhi-Ji QIAN
;
Meng-Jun ZHAO
;
Dong-Hai WU
;
- Publication Type:Journal Article
- Keywords:
Still's disease,adult-onset;
Liver diseases
- From:
Chinese Journal of Rheumatology
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
1000 IU/L,TBil 40～250 mg/L,and mild liver dysfunction at beginning of the disease,but acute severe hepatic lesion occurred due to the use of antibiotics,immunodepressant or NSAIDs.Three patients developed liver function failure and died,7 patients' liver function recovered to nor- mal by increasing dosage of glucocorticoid.Conclusion AOSD with mild liver dysfunction is frequently en- countered.During the treatment,acute severe hepatic lesion may occur due to certain drugs.Therefore,any drug used in AOSD with mild liver dysfunction should be cautious.Once acute severe hepatic lesion happens, increases the dosage of glucocorticoid promptly can improve prognosis.
