Clinical Analysis of 15 Cases of Levobupivacaine Spinal Anesthesia
- VernacularTitle:左旋布比卡因腰麻15例临床分析
- Author:
Wu YIN
;
Lihong CHEN
;
Guilin XIONG
;
- Publication Type:Journal Article
- Keywords:
Levobupivacaine;
Bupivacaine;
Subarachnoid block
- From:
Chinese Journal of Pharmacoepidemiology
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical safety and effectiveness of heavy specific gravity levobupivacaine in spinal block.Method:30 selective general surgical patients of ASAⅠ～Ⅱin obstetrics and gynecology were randomly di- vided into levobupivacaine group(L group)and bupivacaine group(B group).After opening the venous channel and transfusing equilibrium liquid 30 mins,the T 4-5 space was selected as the puncture site for the epidural puncture.The 2 medicaments were injected in the rate of 0.1 ml/s respectively.Then the anesthetizing onset time,maintenance time,time of motion blockade and restoration,effect of anesthesia,variations of blood pressure and heart rate and adverse drug reac- tion were observed.Result:The onset time was 82.61?22.10 s in L group and 59.30?21.50s in B group,respectively. The variations of SBP,DBP and HR in L group were less than those in B group.There was no significant difference in the 2 groups in maintenance time,time of motion blockade and restoration and effect of anesthesia.Conclusion:Compared with bupivacaine,heavy specific gravity levobupivacaine can make the same anesthesia effect with a steadier blood circulation. The specific gravity levobupivacaine is a safe and feasible drug for spinal anesthesia.
