Prognostic factors of cervical high-grade squamous intraepithelial lesions treated by cold knife conization with negative margin
- VernacularTitle:冷刀锥切术切缘阴性的重度宫颈鳞状上皮内瘤变患者的预后影响因素分析
- Author:
Qing-Wei MENG
;
Zhen-He QIN
;
Ying MAO
;
Xiao-Dong ZHAO
;
- Publication Type:Journal Article
- Keywords:
Cervical intrapithelial neoplasia;
Cervix neoplasms;
Neoplasm recurrence;
local;
Surgical procedures;
elective;
Conization
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognostic factors of cervical high-grade squamous intraepithelial lesions treated by cold knife conization with negative margin.Methods Two hundred and sixty-six women with cervical high-grade squamous intraepithelial lesions treated by cold-knife conization with negative margins at Beijing Hospital between Jan 1999 and Jan 2004 were analyzed retrospectively.All patients were followed up with cytology,high-risk human papillomavirus(HPV)test and eolposcopy if necessary.Results The cervical CIN recurrence rate was 8.6% with no incidence of invasive cervical cancer after a median follow-up of 46 months.The recurrence was related to the grade of lesions and gland involvement pathologically.One of 20(5.0%)cases with cervical intraepithelial neoplasia(CIN)Ⅱ,9 of 164(5.5%)cases with CIN Ⅲ(excluding carcinoma in situ,CIS)and 13 of 82(15.8%)cases with CIS recurred(P
