Study on interventional methods and the pattern of maternal-fetal transmission of syphilis during pregnancy
- VernacularTitle:妊娠合并梅毒患者的母婴传播规律与干预方法
- Author:
Rong-Lian ZHANG
;
Qi-Yan CHEN
;
Lie-Ping CHEN
;
Xiu-Yun WANG
;
Li-Ping ZHANG
;
Xiao-Yan XIU
;
Na YANG
;
Xiao-Zhen BAO
;
- Publication Type:Journal Article
- Keywords:
Syphilis;
Pregnancy complications;
infectious;
Disease transmission;
vertical;
Penicillin G;
procaine;
Erythromycin
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the maternal-fetal transmission patterns and interventional methods of syphilis during pregnancy.Methods A total of 847 cases of syphilis in pregnancy confirmed by rapid plasma reagin test(RPR)and treponema pallidum hemoagglutination test(TPHA)were treated with procaine benzylpenieillin intramuscular injection,and with erythrocin oral medication if hypersensitive to benzylpenicillin.Eight hundred forty seven cases of syphilis during pregnancy were followed up for pregnancy outcomes.And their newborn babies were tested using the RPR.The newborns with positive results were given intervention and followed up until 24 months after birth.Results(1)A total of 733 cases among the total 847 have given birth to living-babies,in which 626 cases were tested using RPR,and the positive rate was 55.1%(345/626).(2)The RPR positive rate,neonatal mortality,preterm birth rate and low birth rate in the newborn of mothers with an RPR titer higher than or at 1:8 were higher than those of mothers with an RPR titer lower than 1:8(P
