Anti-mutated citrumnated vimentin antibodies in the diagnosis of rheumatoid arthritis
- VernacularTitle:抗突变型瓜氨酸化波形蛋白抗体检测在类风湿关节炎中的意义
- Author:
Hong ZHANG
;
Xiang-Pei LI
;
Guo-Sheng WANG
;
Long QIANG
;
Wei WANG
;
Lei CHEN
;
- Publication Type:Journal Article
- Keywords:
Arthritis,rheumatoid;
Rheumatoid factors;
Anti-cyclic citrullinated peptide antibodies;
Anti-mutated citrullinated vimentin antibodies
- From:
Chinese Journal of Rheumatology
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the diagnostic value of anti-mutated citrullinated vimentin(anti- MCV)antibodies for rheumatoid arthritis(RA).Methods The anti-MCV were determined in 136 patients with RA,80 non-RA patients and 19 normal peoples.The diagnostic value of anti-MCV was assessed and compared with anti-CCP,AKA and RF.Results The sensitivity and specificity of anti-MCV in the 136 RA patients was 95.6% and 80.8% respectively,there was significanl difference between the test group and the control group(P