Significance of detection of anti-SmD1 antibody in systemic lupus erythematosus
- VernacularTitle:SmD1抗体检测在系统性红斑狼疮诊断中的意义
- Author:
Yong-Feng ZHANG
;
Yi ZHENG
;
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Autoantibodies,anti-StuD1 antibody;
Anti-SSA60 000 antibody
- From:
Chinese Journal of Rheumatology
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of anti-SmD1 antibody and other auto-antibod- ies in systemic lupus erythematosus(SLE).Methods Forty-four SLE patients and 136 other rheumatic dis- eases patients were studied.The later group included Sj(?)gren's syndrome,undifferentiated connective tissue disease,ankylosing spondylitis,and rheumatoid arthritis.Immunoblotting was used to measure,the anti-SmD1 antibody,ANuA and anti-SSA60 000 antibody.ANA and anti-dsDNA were detected by indirect immunofluo- rescence,immunodotting was used to measure the anti-Sin antibody.Results The seropositive rate of anti- StuD1 was 47.7% in SLE patients.It was much higher than that of anti-Sm(P
