Changes of event-related potentials P300 in patients with vascular dementia before and after medical treat-ment
- VernacularTitle:血管性痴呆患者治疗后P300的变化
- Author:
Ruo-Xiao HU
;
Wang-Qiang LU
;
Wei-Xing FAN
;
Xing-Shi CHEN
;
- Publication Type:Journal Article
- Keywords:
Vascular dementia;
P300;
Cognitive dysfunction
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of event-related potentials P300 in evaluation of the cognitive function of patients with vascular dementia (VD).Methods P300 test and Mini-Mental State Examination (MMSE) assessment were carried out in 31 patients with VD before and after 16 weeks of treatment with the oral in- take of donepezil hydrochloride,30 age-matched normal subjects served as the controls.Results Before treatment, the score of MMSE in the VD patients was significantly lower than that in the control group (P
