Effects of movement exercise combined with electroacupuncture on expression of Nestin in hippocampus den-tate gyrus after cerebral ischemia-reperfusion
- VernacularTitle:运动训练结合电针治疗对脑缺血再灌注大鼠海马齿状回区巢蛋白表达的影响
- Author:
Min LU
;
Su-Ming ZHANG
;
Li-Ying CHANG
;
Yi-Hui WANG
;
Chen CHEN
;
Zhou ZHU
;
- Publication Type:Journal Article
- Keywords:
Cerebral isehemia-reperfusion;
Movement exercise;
Eelectroaeupuncture;
Nestin
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of movement exercise combined with electroaeupuneture on the expression of Nestin in the hippocampus dentate gyrus (DG) after cerebral ischemia-repeffusion.Methods Fifty- four Wistar rats were used and randomly divided into a control group (Group A),an exercise training group (Group B),and an exercise training combined with electroacupuncture group (Group C).The middle cerebral arteries (MCA) of all the rats were occluded for 1 h,followed by reperfusion for 7,14 and 21 davs.Immunohistochemistry method was used to detect the expression of Nestin in the hippoeampus dentate gyrus.Results The number of Nes- tin-positive cells peaked in DG in all groups on the 7th day after cerebral isehemia-reperfusion.The number of Nes- tin-positive cells in DG ipsilateral to the ischemia-reperfusion lesion were significantly more than those in the opposite side at various time points (P
