Clinical analysis of 7 dermatomyositis cases with acute interstitial pneumonia and literature review
- VernacularTitle:皮肌炎合并急性间质性肺炎七例临床分析并文献复习
- Author:
Qiang-Hua WEI
;
Yu-Li JIN
;
Hu-Tian YANG
;
Xin ZHOU
;
- Publication Type:Journal Article
- Keywords:
Dematomyositis;
Diagnosis;
Therapy;
Interstitial pneumonia;
acute
- From:
Chinese Journal of Rheumatology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analysis the clinical features of dermatomyositis(DM)complicated with acute interstitial pneumonia(AIP),and to explore the cause of the disease to improve the treatment.Methods Seven cases of dermatomyositis complicated with AIP in our hospital from 1997 to 2005 were studied retro- spectively and the literatures were reviewed.Resets Seven dermatomyositis patients had typical cutaneous vasculitis with slight symptom of myositis.The electromyogram showed myogenic damage.The Jo-I antibodies were all negative.Simultaneously or shortly after the diagnosis of dermatomyositis,all patients presented with high fever,dry cough and progressed dyspnea.The chest X-ray or high-resolution computed tomography dis- played diffuse pulmonary interstitial changes which progressed rapidly.All patients died despites anti-infec- tious treatment and high dose steroid therapy.Conclusion AIP is the pulmonary injury of amyopathic or hy- pomyopathic dermatomyositis.In order to improve the prognosis,early diagnosis should be emphasized and in- terdisciplinary cooperation should be strengthened.
