The comparison of efficacy of different dosage regimen of recombinant human tumor necrosis factor receptor-Fc fusion protein in Chinese ankylosing spondylitis patients
- VernacularTitle:不同剂量重组人Ⅱ型肿瘤坏死因子受体-Fc融合蛋白治疗强直性脊柱炎疗效比较
- Author:
Hui-Qin HAO
;
Feng HUANG
;
Jie TANG
;
Xiao-Hu DENG
;
Ya-Mei ZHANG
;
Ta-Lin SUO
;
Xian-Feng FANG
;
- Publication Type:Journal Article
- Keywords:
Spondylitis,ankylosing;
Tumor necrosis factor-alpha;
Treatment outcome
- From:
Chinese Journal of Rheumatology
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).In addition,in different medication intervals and the same total dosage(200 mg),there was no difference in the number of patients who reached ASAS20,ASAS50 anti BASDAI50 in both groups.The changes of other parameters were not observed.Conclusion Two dosages and different medication interval of rhTNFR-Fc have similiar efficacy onset time and maintenee period.Mean- while,at the same total dosage,there is no signifieant difference in therapeutic effect in the two dosage groups. However,50 mg(1/7 d)regimen has better compliance than 25 mg(1/3 d).
