Autologous peripheral blood stem cell transplantation for systemic lupus erythematosns
- VernacularTitle:自体外周血造血干细胞移植治疗系统性红斑狼疮的临床观察
- Author:
Shao-Xian HU
;
Ji-Ping WU
;
Xiao-Mei LEI
;
Wei TU
;
Shou-Xin LI
;
Dong-Hua ZHANG
;
Yi-Cheng ZHANG
;
Wei HUANG
;
Yi XIAO
;
Peigen HE
;
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Meta-analysis;
Autologous peripheral blood stem cell transplantation
- From:
Chinese Journal of Rheumatology
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
20?10~9/L.The proteinuria decreased or disappeared.The antinuclear antibody decreased or became negative.The level of complement was increased.The following complications were ob- served:septicemia in 2 patients,cytomegalovirus infection in 2 patients,renal toxicity in 1 patient,acute left heart failure in 3 patients and cardiac arrhythmia in 3 patients.There was no transplantation related mortality. Conclusion APBSCT may improve the disease activity and the immunological markers in SLE.It is a valid therapy for refractory SLE,but the long-term effects need to be observed.
