Relationship between the expression of P-glycoprotein,glutathione S-transferase-? and thymidylate synthase proteins and adenosine triphosphate tumor chemosensitivity assay in cervical cancer
- VernacularTitle:子宫颈癌组织三磷酸腺苷肿瘤体外药物敏感试验及其与耐药蛋白表达的关系
- Author:
Guo-Lan GAO
;
Hong-Ying WAN
;
Xue-Sen ZOU
;
Wen-Xue CHEN
;
Yue-Qing CHEN
;
Xiu-Zhen HUANG
;
- Publication Type:Journal Article
- Keywords:
Cervix neoplasms;
P-Glycoprotein;
Glutathione transferase;
Thymidylate synthase;
Adenosine triphosphate;
Drug screening assays;
antitumor
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).Conclusions ATP-TCA could be used to individualize chemotherapy by selecting agents for particular patients of cervical cancer.The expression of GST-? and TS protein might be useful biomarkers to predict the resistance to DDP and 5-FU in patients with cervical cancer.
