Study on the expression of transcription factor GATA-3 and T-bet mRNA in decidua of women with unexplained recurrent spontaneous abortion
- VernacularTitle:原因不明复发性流产患者蜕膜组织中转录因子GATA-3及T-bet mRNA表达的研究
- Author:
Li-Hua QIU
;
Qi-De LIN
;
- Publication Type:Journal Article
- Keywords:
Abortion;
habitual;
DNA-binding proteins;
Trans-activators;
T-lymphocytes;
helper-inducer
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the roles of transcription factor GATA-3 and T-bet at the fetal- maternal interface in the pathogenesis of unexplained recurrent spontaneous abortion(URSA).Methods The expression of GATA-3 and T-bet mRNA was examined by in situ hybridization.Decidua was obtained from 20 women with URSA and 20 normal pregnant(NP)women.Results(1)The number of GATA-3 positive cells per high power field in women with URSA(25?16)was significantly lower than those in NP women(38?16)(P
