Effect of Tangmoning Granule in Treating Diabetic Peripheral Neuropathy with Qi-deficiency and Collateral Stagnation Syndrome:An Observation of 432 Cases
- VernacularTitle:糖末宁颗粒治疗糖尿病性周围神经病变(气虚络阻证)432例临床研究
- Author:
Qiu'Ai KOU
;
Guangde ZHANG
;
Zixiao WEI
;
Tao LI
;
- Publication Type:Journal Article
- Keywords:
Tangmoning Granule;
Diabetic peripheral neuropathy;
Qi-deficiency and collateral stagnation syndrome;
Clinical trial
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy and safety of Tangmoning Granule(TMG)in treating diabetic peripheral neuropathy with Qi-deficiency and collateral stagnation syndrome.Methods A randomized,positive drug parallel controled,multi-center clinical trial was adopted.The tested group was treated with TMG orally and the control group received Mikebao tablet orally.Treatment course of each group was 8 weeks.Results The marked effective rate and total effective rate on electromyogram was 60.06 %and 68.47 %respectively in the tested group,and those on TCM Syndrome were 23.12 %and 90.99 %respectively.Non-inferiority test with the criterion of 15 %was conducted on the efficacy of electromyogram and TCM Syndrome,and the result showed statistical significant.Conclusion TMG has good efficacy and safety in treating diabetic peripheral neuropathy with Qi-deficiency and collateral stagnation syndrom.
